Fecal Colonization With Multidrug-Resistant E. coli Among Healthy Infants in Rural Bangladesh

Authors: Mohammad Aminul Islam, Mohammed Badrul Amin1, Subarna Roy, Muhammad Asaduzzaman, Md. Rayhanul Islam, Tala Navab-Daneshmand, Mia Catharine Mattioli, Molly L. Kile, Karen Levy and Timothy R. Julian.

The rapid rise of multidrug-resistant bacterial infections is a major public health concern and a growing threat to the global health security. The unregulated use of broad spectrum antibiotics and widespread reservoirs of these pathogens are the main contributors to this problem. Broad spectrum antibiotics, in particular third generation cephalosporins (3GC), are among the most frequently prescribed drugs for the treatment of infections caused by Enterobacteriaceae. Due to their overuse, an increasing trend of resistance to 3GC has been observed in developing countries. In this article, the authors describe fecal colonization of 3GC-resistant Escherichia coli in healthy infants (1–12 months old) living in rural areas of Bangladesh.

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